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Peak Plasma Time: 10-60 min (PO immediate-release); 60-120 min (PO extended-release); 6 hr (PO 500 mg, conventional tablet); 8 hr (PO 650 mg, extended-release tablet) Peak Plasma Concentration: 2. harga obat pyrazinamide 500 mg 1 mcg/mL (PO 500 mg, conventional tablet); 1 8 mcg/mL (PO 650 mg, extended-release tablet) Onset: 1 hr Distribution: 1 L/kg Protein Bound: 10 to 25%